The most popular undergraduate major at South Dakota State University is Registered Nursing/Registered Nurse followed by Biology/Biological Sciences and Economics. A list of all 71 available majors and annual graduates is presented below. Also of interest, median earnings for South Dakota State University graduates by major.
| Agriculture | 30 |
Agriculture |
Graduates |
| Agribusiness/Agricultural Business Operations | 41 |
| Agricultural Economics | 3 |
| Agricultural Mechanization | 12 |
| Applied Horticulture/Horticulture Operations | 9 |
| Landscaping and Groundskeeping | 9 |
| Agricultural Communication/Journalism | 3 |
| Animal Sciences | 71 |
| Dairy Science | 20 |
| Agronomy and Crop Science | 29 |
| Range Science and Management | 9 |
Computer and Information Sciences |
Graduates |
| Computer and Information Sciences | 20 |
Education |
Graduates |
| Early Childhood Education and Teaching | 41 |
| Agricultural Teacher Education | 12 |
| Music Teacher Education | 15 |
| Technical Teacher Education | 1 |
Engineering |
Graduates |
| Agricultural Engineering | 11 |
| Civil Engineering | 26 |
| Computer Software Engineering | 6 |
| Electrical and Electronics Engineering | 19 |
| Mechanical Engineering | 42 |
Engineering Technology |
Graduates |
| Electrical, Electronic and Communications Engineering Technology/Technician | 16 |
| Manufacturing Engineering Technology/Technician | 21 |
| Construction Engineering Technology/Technician | 44 |
| Engineering/Industrial Management | 10 |
Foreign Languages |
Graduates |
| German Language and Literature | 4 |
| French Language and Literature | 2 |
| Spanish Language and Literature | 29 |
Work and Family Studies |
Graduates |
| Family Resource Management Studies | 5 |
| Consumer Economics | 48 |
| Foods, Nutrition, and Wellness Studies | 29 |
| Human Development and Family Studies | 30 |
| Apparel and Textile Marketing Management | 9 |
English and Literature |
Graduates |
| English Language and Literature | 13 |
| Rhetoric and Composition | 14 |
Liberal Arts and Humanities |
Graduates |
| Liberal Arts and Sciences/Liberal Studies | 24 |
| General Studies | 19 |
Biology |
Graduates |
| Biology/Biological Sciences | 88 |
| Biochemistry | 3 |
| Microbiology | 14 |
Mathematics |
Graduates |
| Mathematics | 15 |
Natural Resources Conservation |
Graduates |
| Natural Resources Management and Policy | 4 |
| Wildlife, Fish and Wildlands Science and Management | 43 |
General Studies |
Graduates |
| International/Global Studies | 13 |
Recreation, Leisure and Fitness Studies |
Graduates |
| Parks, Recreation and Leisure Facilities Management | 17 |
| Health and Physical Education/Fitness | 34 |
| Health and Physical Education/Fitness, Other | 15 |
Physical Sciences |
Graduates |
| Chemistry | 6 |
| Physics | 1 |
Psychology |
Graduates |
| Psychology | 41 |
Social Sciences |
Graduates |
| Economics | 73 |
| Geography | 11 |
| Geography, Other | 7 |
| Political Science and Government | 17 |
| Sociology | 62 |
Transportation and Materials Moving |
Graduates |
| Aeronautics/Aviation/Aerospace Science and Technology | 2 |
| Aviation/Airway Management and Operations | 8 |
| Flight Instructor | 6 |
Visual and Performing Arts |
Graduates |
| Visual and Performing Arts | 10 |
| Interior Design | 11 |
| Graphic Design | 20 |
| Music | 2 |
| Music Management | 1 |
Health Professions |
Graduates |
| Athletic Training/Trainer | 15 |
| Clinical Laboratory Science/Medical Technology/Technologist | 11 |
| Pharmaceutics and Drug Design | 66 |
| Registered Nursing/Registered Nurse | 287 |
Business |
Graduates |
| Entrepreneurship/Entrepreneurial Studies | 4 |
| Hotel/Motel Administration/Management | 9 |
History |
Graduates |
| History | 39 |
Communication |
Graduates |
| Journalism | 49 |
Primary data source, U.S. Department of Education https://nces.ed.gov/collegenavigator/?id=219356 IPEDS survey data for South Dakota State University.